Longevity & immune
SS-31
Written by the Elevate Clinical Team
Citations independently verified against PubMed, ClinicalTrials.gov, and FDA sources on . Independent clinical review pending.
Also known as Elamipretide
A mitochondria-targeted peptide studied for cardiolipin stabilization and cellular energy production.
What it is
SS-31 concentrates in the inner mitochondrial membrane and binds cardiolipin, a lipid essential to the electron transport chain. Stabilizing it improves ATP production efficiency and reduces reactive oxygen species in models of mitochondrial dysfunction. It has reached clinical trials for rare mitochondrial disease.
What it's studied for
- Primary mitochondrial myopathy trials
- Barth syndrome and dry age-related macular degeneration
- Heart-failure and skeletal-muscle energetics
How it's used in practice
- An investigational drug in active clinical development, not a wellness compound
- Trial results have been mixed on primary endpoints
What you should know before asking about it
- Not FDA-approved; research use only
- No established protocol outside of clinical trials
Frequently asked questions.
- What is SS-31?
- SS-31 concentrates in the inner mitochondrial membrane and binds cardiolipin, a lipid essential to the electron transport chain. Stabilizing it improves ATP production efficiency and reduces reactive oxygen species in models of mitochondrial dysfunction. It has reached clinical trials for rare mitochondrial disease.
- What is SS-31 studied for?
- Published and ongoing research looks at primary mitochondrial myopathy trials; barth syndrome and dry age-related macular degeneration; heart-failure and skeletal-muscle energetics. These are areas of study, not promised outcomes.
- Is SS-31 FDA-approved?
- SS-31 has not been evaluated by the FDA. Elevate Chicago lists it for education and research reference only — it is not prescribed as medical care and is not intended for human consumption.
- How is SS-31 typically used?
- An investigational drug in active clinical development, not a wellness compound Trial results have been mixed on primary endpoints Any specific dose, frequency or duration comes from a prescription written for you after labs — never from this page.
- What are the risks and unknowns with SS-31?
- Not FDA-approved; research use only No established protocol outside of clinical trials
Sources
- 1.Published literature on SS-31 Elamipretide— PubMed, U.S. National Library of Medicine
- 2.Compounding and the FDA: questions and answers— U.S. Food & Drug Administration
- 3.Bulk drug substances nominated for use in compounding under section 503A— U.S. Food & Drug Administration
- 4.Test directory and patient service center locator— Quest Diagnostics
About this page
Written by the Elevate Clinical Team
Citations independently verified against PubMed, ClinicalTrials.gov, and FDA sources on . Independent clinical review pending. Educational content only — not medical advice, not a diagnosis, and not an offer to sell any prescription product.
This page is educational reference material. It is not medical advice, not a diagnosis, and not an offer to sell any product. Prescription therapies are dispensed only through licensed, FDA-registered compounding pharmacies after a physician evaluation. Compounds identified as research use only are not FDA-approved, are not prescribed as medical care, and are not intended for human or animal consumption. Availability, formulations and regulatory status change over time.
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