Longevity & immune
Humanin.
Written by the Elevate Clinical Team
Medically reviewed by Dr. Eric W. Anderson, MD · Last reviewed
Citations independently verified against PubMed, ClinicalTrials.gov, and FDA sources on .
A mitochondrial-derived peptide studied for cytoprotection, insulin sensitivity and neuroprotection.
What it is
Humanin was the first mitochondrial-derived peptide identified, found in a screen for factors protecting neurons from Alzheimer's-related toxicity. Circulating levels decline with age and correlate with markers of healthspan in observational work.
What it's studied for
- Neuroprotection in Alzheimer's models
- Insulin sensitivity and IGF-1 interaction
- Cardiovascular and endothelial protection in animal models
How it's used in practice
- Preclinical and observational research; no human dosing standard exists
What you should know before asking about it
- Research use only; not FDA-approved
- No human trials establishing safety or efficacy
Frequently asked questions.
- What is Humanin?
- Humanin was the first mitochondrial-derived peptide identified, found in a screen for factors protecting neurons from Alzheimer's-related toxicity. Circulating levels decline with age and correlate with markers of healthspan in observational work.
- What is Humanin studied for?
- Published and ongoing research looks at neuroprotection in Alzheimer's models; insulin sensitivity and IGF-1 interaction; cardiovascular and endothelial protection in animal models. These are areas of study, not promised outcomes.
- Is Humanin FDA-approved?
- Humanin has not been evaluated by the FDA. Elevate Chicago lists it for education and research reference only — it is not prescribed as medical care and is not intended for human consumption.
- How is Humanin typically used?
- Preclinical and observational research; no human dosing standard exists. Any specific dose, frequency or duration comes from a prescription written for you after labs — never from this page.
- What are the risks and unknowns with Humanin?
- Research use only; not FDA-approved. No human trials establishing safety or efficacy.
Sources
- 1.Published literature on Humanin— PubMed, U.S. National Library of Medicine
- 2.Compounding and the FDA: questions and answers— U.S. Food & Drug Administration
- 3.Bulk drug substances nominated for use in compounding under section 503A— U.S. Food & Drug Administration
- 4.Test directory and patient service center locator— Quest Diagnostics
About this page
Written by the Elevate Clinical Team
Medically reviewed by Dr. Eric W. Anderson, MD · Last reviewed . Citations independently verified against PubMed, ClinicalTrials.gov, and FDA sources on . Educational content only — not medical advice, not a diagnosis, and not an offer to sell any prescription product.
This page is educational reference material. It is not medical advice, not a diagnosis, and not an offer to sell any product. Prescription therapies are dispensed only through licensed, FDA-registered compounding pharmacies after a physician evaluation. Compounds identified as research use only are not FDA-approved, are not prescribed as medical care, and are not intended for human or animal consumption. Availability, formulations and regulatory status change over time.
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