Sleep, cognition & neuro

Semax

Written by the Elevate Clinical Team

Citations independently verified against PubMed, ClinicalTrials.gov, and FDA sources on . Independent clinical review pending.

See the FDA 503A status tracker

An ACTH(4-10) analog studied for attention, memory and neuroprotection.

What it is

Semax is a modified fragment of ACTH stripped of its hormonal activity, developed in Russia for stroke and cognitive indications. Research focuses on BDNF and NGF expression and on dopaminergic and serotonergic modulation.

What it's studied for

  • Cognitive performance and attention measures
  • Neuroprotection in ischemic-stroke research
  • BDNF and NGF expression

How it's used in practice

  • Intranasal administration is standard in the literature
  • Reported effects are subtle and short-acting rather than stimulant-like

What you should know before asking about it

  • Research use only in the United States; not FDA-approved
  • Evidence base is largely non-Western and hard to independently verify

Frequently asked questions.

What is Semax?
Semax is a modified fragment of ACTH stripped of its hormonal activity, developed in Russia for stroke and cognitive indications. Research focuses on BDNF and NGF expression and on dopaminergic and serotonergic modulation.
What is Semax studied for?
Published and ongoing research looks at cognitive performance and attention measures; neuroprotection in ischemic-stroke research; bDNF and NGF expression. These are areas of study, not promised outcomes.
Is Semax FDA-approved?
Semax has not been evaluated by the FDA. Elevate Chicago lists it for education and research reference only — it is not prescribed as medical care and is not intended for human consumption.
How is Semax typically used?
Intranasal administration is standard in the literature Reported effects are subtle and short-acting rather than stimulant-like Any specific dose, frequency or duration comes from a prescription written for you after labs — never from this page.
What are the risks and unknowns with Semax?
Research use only in the United States; not FDA-approved Evidence base is largely non-Western and hard to independently verify

Sources

  1. 1.Published literature on SemaxPubMed, U.S. National Library of Medicine
  2. 2.Compounding and the FDA: questions and answersU.S. Food & Drug Administration
  3. 3.Bulk drug substances nominated for use in compounding under section 503AU.S. Food & Drug Administration
  4. 4.Test directory and patient service center locatorQuest Diagnostics

About this page

Written by the Elevate Clinical Team

Citations independently verified against PubMed, ClinicalTrials.gov, and FDA sources on . Independent clinical review pending. Educational content only — not medical advice, not a diagnosis, and not an offer to sell any prescription product.

This page is educational reference material. It is not medical advice, not a diagnosis, and not an offer to sell any product. Prescription therapies are dispensed only through licensed, FDA-registered compounding pharmacies after a physician evaluation. Compounds identified as research use only are not FDA-approved, are not prescribed as medical care, and are not intended for human or animal consumption. Availability, formulations and regulatory status change over time.