Growth hormone secretagogues

CJC-1295

Written by the Elevate Clinical Team

Citations independently verified against PubMed, ClinicalTrials.gov, and FDA sources on . Independent clinical review pending.

Also known as with or without DAC

A GHRH analog with extended half-life, studied to raise baseline growth-hormone and IGF-1 signaling.

What it is

CJC-1295 is a modified GHRH analog. The DAC (drug affinity complex) version binds albumin and lasts for days, raising baseline GH; the version without DAC — often called modified GRF (1-29) — acts in a short pulse closer to natural physiology.

What it's studied for

  • Sustained IGF-1 elevation in early human trials
  • Combined effect with ghrelin-receptor agonists like Ipamorelin
  • Body composition and recovery signaling

How it's used in practice

  • DAC and non-DAC behave very differently; they are not interchangeable
  • IGF-1 monitoring is how response and overshoot are tracked

What you should know before asking about it

  • Availability varies and formulations change; not all versions are pharmacy-available
  • Contraindicated with active malignancy
  • Water retention, joint discomfort and carpal-tunnel-type symptoms are dose-related signals to reduce

Frequently asked questions.

What is CJC-1295?
CJC-1295 is a modified GHRH analog. The DAC (drug affinity complex) version binds albumin and lasts for days, raising baseline GH; the version without DAC — often called modified GRF (1-29) — acts in a short pulse closer to natural physiology.
What is CJC-1295 studied for?
Published and ongoing research looks at sustained IGF-1 elevation in early human trials; combined effect with ghrelin-receptor agonists like Ipamorelin; body composition and recovery signaling. These are areas of study, not promised outcomes.
Is CJC-1295 FDA-approved?
CJC-1295 is not FDA-approved as a finished product. It is prepared by licensed, FDA-registered compounding pharmacies and can be dispensed only on a prescription written after a physician evaluation.
How is CJC-1295 typically used?
DAC and non-DAC behave very differently; they are not interchangeable IGF-1 monitoring is how response and overshoot are tracked Any specific dose, frequency or duration comes from a prescription written for you after labs — never from this page.
What are the risks and unknowns with CJC-1295?
Availability varies and formulations change; not all versions are pharmacy-available Contraindicated with active malignancy Water retention, joint discomfort and carpal-tunnel-type symptoms are dose-related signals to reduce

Sources

  1. 1.Published literature on CJC-1295 with or without DACPubMed, U.S. National Library of Medicine
  2. 2.Compounding and the FDA: questions and answersU.S. Food & Drug Administration
  3. 3.Bulk drug substances nominated for use in compounding under section 503AU.S. Food & Drug Administration
  4. 4.Test directory and patient service center locatorQuest Diagnostics

About this page

Written by the Elevate Clinical Team

Citations independently verified against PubMed, ClinicalTrials.gov, and FDA sources on . Independent clinical review pending. Educational content only — not medical advice, not a diagnosis, and not an offer to sell any prescription product.

This page is educational reference material. It is not medical advice, not a diagnosis, and not an offer to sell any product. Prescription therapies are dispensed only through licensed, FDA-registered compounding pharmacies after a physician evaluation. Compounds identified as research use only are not FDA-approved, are not prescribed as medical care, and are not intended for human or animal consumption. Availability, formulations and regulatory status change over time.